With over 1,000 genomes sequenced and over 40 million variants discovered, the research will lay a foundation for biomedical and precision medicine development, contributing to giving early treatment to each Vietnamese individual in the future.
The first database of its kind also has enough annotations about biological functions and pathological risks.
Prof. Ta Thanh Van, Chairman of the Council of Hanoi Medical University, said the database will provide an invaluable reference to improve the efficiency of diagnosis and treatment in the country.
Launched in December 2018, the project drew the participation of over 40 scientists from leading universities and units worldwide as well as hundreds of experts and volunteers at home and abroad.
During three years, they sequenced genomes of over 1,000 unrelated adults aged 35-55 and discovered more than 40 million genetic variants, nearly 2 million of them are representative of the Vietnamese population. The process was made at a lab meeting ISO 15189 standards at Vinmec International General Hospital, using advanced technologies by Google, Illumina and NVIDIA.
Part of the database is now available at https://genome.vinbigdata.org. Several hi-speed analysis tools are also offered on trial there.
The pioneering project costs over 4.5 million USD, the largest scale in Vietnam so far.
