A North-South SE1 train hit a four-seater car, when it was crossing DH10 road in Binh Chanh Ward in the province's Thang Binh District.
Fifty-year-olds Nguyen Cong Tien, deputy manager of Thang Binh department of education, and Tran Ngoc Thanh, a teacher, were killed in the accident. Both were residents of Thang Binh District's Ha Lam Town.
The district and provincial police rushed to the site to investigate the accident.
The injured victim was taken into Quang Nam General Hospital.
Phan Thanh Hong, deputy chief of the province's traffic police office, said the accident occurred in a residential area, where there were no barricades and automated railway signs.
The local authorities had reported the problems to the railway sector, but no improvements had been made.
"The train continued its journey after the accident," Hong said. "The cause of the accident is unclear at the moment because the car driver is dead, and one passenger is badly injured."
"We will investigate further to find out why the car did not notice or did not see the train when it crossed the railway track," he said.
In another incident yesterday, a van carrying six passengers fell into a 200m-deep chasm in Cao Bang Province's Ban Diem Commune, killing three people and injuring three.
