Juve, with 18 points from six games, will take a three-point lead into Saturday’s match at home to bitter rivals Napoli after last season’s runners-up comfortably disposed of Parma 3-0 with a brace from striker Arkadiusz Milik.
Bologna produced a shock win over Roma at the weekend but their resistance lasted only 12 minutes against the defending champions, who are aiming for an eighth successive Serie A title.
Dybala set up Blaise Matuidi for a shot which was parried by goalkeeper Lukasz Skorupski and the Argentine followed up to score from the rebound, his first Juventus goal since May 5, which was coincidentally against the same opponents.
Dybala also had a hand in the second four minutes later, his cross finding Cristiano Ronaldo for the Portuguese to knock back across the goal where Matuidi scored from a difficult angle.
Napoli’s win was equally straightforward after Lorenzo Insigne gave them a fourth-minute lead against promoted Parma.
Milik fired in from long range early in the second half and the Pole turned in the third from close range in the 87th minute to give Carlo Ancelotti’s team a fifth win in six games.
New signings Joaquin Correa and Francesco Acerbi scored to give Lazio a 2-1 win at Udinese which kept them third, three points behind Napoli.
Acerbi, signed from Sassuolo, turned in a rebound on the hour and Argentine midfielder Correa got off the mark following his move from Sevilla with a solo goal six minutes later.
Lazio had to cling on, however, after Bram Nuytinck pulled one back with an overhead kick with 10 minutes left.
AS Roma ended a five-match winless run in all competitions by thumping Frosinone 4-0 with Cengiz Under, Javier Pastore, Stephan El Shaarawy and Aleksandar Kolarov sharing the goals.
Under rifled in a long-range effort after two minutes, Pastore back-heeled the second and El Shaarawy tapped in from Under’s assist for the third after only 35 minutes. Kolarov capped the win three minutes from fulltime.
Promoted Frosinone have yet to score a goal and have leaked 16 in their six games, although they have one point.
Genoa beat bottom club Chievo 2-0 while Atalanta-Torino and Cagliari-Sampdoria matches ended goalless.