The smuggled goods included more than 2kg of heroin, 2.58kg of methamphetamines, 1.8kg of cocaine, 372.7kg of ivory and 105 elephant tusks.
Popular smuggled goods transported by air also include wild animals, gold and weapons.
The department said smuggling and the illegal transport of goods by air have become more complicated in recent years, particularly at international airports such as Nội Bài Airport in Hà Nội, Tân Sơn Nhất Airport in HCM City and Đà Nẵng Airport in central Đà Nẵng City.